Coronavirus vaccine test opens as US volunteer gets 1st shot
U.S. researchers gave the first shot to the first person in a test of an experimental coronavirus vaccine Monday 바카라 게임 웹사이트 leading off a worldwide hunt for protection even as the pandemic surges.
With a careful jab in a healthy volunteer바카라 게임 웹사이트s arm, scientists at the Kaiser Permanente Washington Research Institute in Seattle begin an anxiously awaited first-stage study of a potential COVID-19 vaccine developed in record time after the new virus exploded from China and fanned across the globe.
바카라 게임 웹사이트We바카라 게임 웹사이트re team coronavirus now,바카라 게임 웹사이트 Kaiser Permanente study leader Dr. Lisa Jackson said on the eve of the experiment. 바카라 게임 웹사이트Everyone wants to do what they can in this emergency.바카라 게임 웹사이트
The Associated Press observed as the study바카라 게임 웹사이트s first participant, an operations manager at a small tech company, received the injection inside an exam room. Several others were next in line for a test that will ultimately give 45 volunteers two doses, a month apart.
바카라 게임 웹사이트We all feel so helpless. This is an amazing opportunity for me to do something,바카라 게임 웹사이트 said Jennifer Haller, 43, of Seattle.
She's the mother of two teenagers and 바카라 게임 웹사이트they think it's cool바카라 게임 웹사이트 that she's taking part in the study.
Monday바카라 게임 웹사이트s milestone marked just the beginning of a series of studies in people needed to prove whether the shots are safe and could work. Even if the research goes well, a vaccine wouldn바카라 게임 웹사이트t be available for widespread use for 12 to 18 months, said Dr. Anthony Fauci of the U.S. National Institutes of Health. That바카라 게임 웹사이트s still important if the virus becomes a long-term threat.
This vaccine candidate, code-named mRNA-1273, was developed by the NIH and Massachusetts-based biotechnology company Moderna Inc. There바카라 게임 웹사이트s no chance participants could get infected from the shots because they don바카라 게임 웹사이트t contain the coronavirus itself.
It바카라 게임 웹사이트s not the only potential vaccine in the pipeline. Dozens of research groups around the world are racing to create a vaccine against COVID-19. Another candidate, made by Inovio Pharmaceuticals, is expected to begin its own safety study -- in the U.S., China and South Korea -- next month.
The Seattle experiment got underway days after the World Health Organization declared the new virus outbreak a pandemic because of its rapid global spread, infecting more than 169,000 people and killing more than 6,500.
COVID-19 has upended the world바카라 게임 웹사이트s social and economic fabric since China first identified the virus in January, with regions shuttering schools and businesses, restricting travel, canceling entertainment and sporting events, and encouraging people to stay away from each other.
Starting what scientists call a first-in-humans study is a momentous occasion for scientists, but Jackson described her team바카라 게임 웹사이트s mood as 바카라 게임 웹사이트subdued.바카라 게임 웹사이트 They바카라 게임 웹사이트ve been working round-the-clock readying the research in a part of the U.S. struck early and hard by the virus.
Still, 바카라 게임 웹사이트going from not even knowing that this virus was out there ... to have any vaccine바카라 게임 웹사이트 in testing in about two months is unprecedented, Jackson told The AP.
Some of the study바카라 게임 웹사이트s carefully chosen healthy volunteers, ages 18 to 55, will get higher dosages than others to test how strong the inoculations should be. Scientists will check for any side effects and draw blood samples to test if the vaccine is revving up the immune system, looking for encouraging clues like the NIH earlier found in vaccinated mice.
바카라 게임 웹사이트We don바카라 게임 웹사이트t know whether this vaccine will induce an immune response, or whether it will be safe. That바카라 게임 웹사이트s why we바카라 게임 웹사이트re doing a trial,바카라 게임 웹사이트 Jackson stressed. 바카라 게임 웹사이트It바카라 게임 웹사이트s not at the stage where it would be possible or prudent to give it to the general population.바카라 게임 웹사이트
Most of the vaccine research under way globally targets a protein aptly named 바카라 게임 웹사이트spike바카라 게임 웹사이트 that studs the surface of the new coronavirus and lets it invade human cells. Block that protein and people won바카라 게임 웹사이트t get infected.
Researchers at the NIH copied the section of the virus바카라 게임 웹사이트 genetic code that contains the instructions for cells to create the spike protein. Moderna encased that 바카라 게임 웹사이트messenger RNA바카라 게임 웹사이트 into a vaccine.
The idea: The body will become a mini-factory, producing some harmless spike protein. When the immune system spots the foreign protein, it will make antibodies to attack -- and be primed to react quickly if the person later encounters the real virus.
That바카라 게임 웹사이트s a much faster way of producing a vaccine than the traditional approach of growing virus in the lab and preparing shots from either killed or weakened versions of it.
But because vaccines are given to millions of healthy people, it takes time to test them in large enough numbers to spot an uncommon side effect, cautioned Dr. Nelson Michael of the Walter Reed Army Institute of Research, which is developing a different vaccine candidate.
바카라 게임 웹사이트The science can go very quickly but, first, do no harm, right?바카라 게임 웹사이트 he told reporters last week.
The Seattle research institute is part of a government network of centers that test all kinds of vaccines, and was chosen for the coronavirus vaccine study before COVID-19 began spreading widely in Washington state.
Kaiser Permanente screened dozens of people, looking for those who have no chronic health problems and aren바카라 게임 웹사이트t currently sick. Researchers aren바카라 게임 웹사이트t checking whether would-be volunteers already had a mild case of COVID-19 before deciding if they바카라 게임 웹사이트re eligible. If some did, scientists will be able to tell by the number of antibodies in their pre-vaccination blood test and account for that, Jackson said. Participants will be paid $100 for each clinic visit in the study.