Forget TikTok claims: 바카라 게임 웹사이트Nature바카라 게임 웹사이트s Ozempic바카라 게임 웹사이트 is no such thing, experts say
If TikTok and Reddit influencers are to be believed, the plant-based compound called berberine can be a replacement for such popular diabetes and weight loss drugs as Ozempic and Wegovy.
Video above: Could popular weight loss drugs treat addiction?
Using berberine as a supplement has become so trendy, in fact, that it has been dubbed 바카라 게임 웹사이트" by social media users. Some manufacturers are jumping on the trend.
바카라 게임 웹사이트Berberine has become my new BFF because it has been helping me with my weight loss,바카라 게임 웹사이트 one believer gushed, adding that one of the herbal supplement바카라 게임 웹사이트s manufacturers is offering her 바카라 게임 웹사이트 and a few of her lucky viewers 바카라 게임 웹사이트 a year바카라 게임 웹사이트s supply.
Some medical experts CNN spoke with, however, had concerns about the use of this unregulated supplement. As an extract from plants such as goldenseal, barberry and various poppies, berberine is considered a by the US Food and Drug Administration and is thus regulated as a food, not a drug.
바카라 게임 웹사이트That바카라 게임 웹사이트s the problem with berberine and all of these herbal substances 바카라 게임 웹사이트 they바카라 게임 웹사이트re typically not rigorously studied in the type of large, randomized clinical trials that we put actual drugs through. So, you have to be very careful,바카라 게임 웹사이트 said Dr. Caroline Apovian, a professor of medicine at Harvard Medical School and co-director of the Center for Weight Management and Wellness at Brigham and Women바카라 게임 웹사이트s Hospital in Boston.
바카라 게임 웹사이트As for it being nature바카라 게임 웹사이트s Ozempic, there바카라 게임 웹사이트s no evidence to suggest that is true,바카라 게임 웹사이트 added Apovian, who was the lead author for the Endocrine Society바카라 게임 웹사이트s for the pharmacological management of obesity.
Is berberine바카라 게임 웹사이트s weight loss effect meaningful?
That doesn바카라 게임 웹사이트t mean that the herb has no impact at all on the body바카라 게임 웹사이트s metabolic systems, however. A of a number of small clinical studies on berberine바카라 게임 웹사이트s impact on cardiovascular risk factors, including obesity, found a very small, but statistically significant weight loss benefit.
바카라 게임 웹사이트But statistical significance does not mean clinically meaningful,바카라 게임 웹사이트 said Dr. Justin Ryder, a pediatric obesity researcher and associate professor of surgery and pediatrics at Northwestern University바카라 게임 웹사이트s Feinberg School of Medicine in Chicago.
바카라 게임 웹사이트What do I mean by that? On average across the studies, the pooled response was about a 0.25 reduction in or BMI compared to placebo,바카라 게임 웹사이트 he said. Body mass index is a measurement of a person바카라 게임 웹사이트s body fat based on height and weight.
바카라 게임 웹사이트For Ozempic and Wegovy, the decrease in BMI compared to placebo was 4.61 BMI units, or 18 times more effective than berberine, Ryder added. 바카라 게임 웹사이트So, does berberine have an effect? The data would suggest yes. Is the effect meaningful? Probably not.바카라 게임 웹사이트
History of berberine
Some of the roughly 500 different species of plants that belong in the genius Berberis have been used for centuries in Ayurveda and to fight inflammation and heal wounds, cure constipation and hemorrhoids, and battle infections of the ear, eye, mouth and digestive tract.
바카라 게임 웹사이트It바카라 게임 웹사이트s part of the arsenal of herbs used by naturopathic doctors,바카라 게임 웹사이트 said Dr. Joshua Levitt, a in Hamden, Connecticut.
바카라 게임 웹사이트When it comes to glycemic control and for regulation of cholesterol and other lipids and antimicrobial uses, there바카라 게임 웹사이트s some cool stuff to be done with herbs and nutrients.바카라 게임 웹사이트
In fact, the of Assyrian emperor Ashurbanipal has clay tablets dating back to 650 BC stating the tangy fruit of the barberry plant was used as a blood-purifying agent.
바카라 게임 웹사이트It바카라 게임 웹사이트s usually used in its whole plant extract form 바카라 게임 웹사이트 leaves, roots, bark all made into a tincture powder or something,바카라 게임 웹사이트 Levitt said.
Scientists were able to extract berberine as the active ingredient in these plants over 100 years ago, he said, and began to study the compound for metabolic issues such as cholesterol, diabetes and obesity.
Berberine may enhance the body바카라 게임 웹사이트s natural production of , or glucagon-like peptide 1, a gastrointestinal hormone that바카라 게임 웹사이트s used in Ozempic and other new weight loss drugs. That바카라 게임 웹사이트s how the compound 바카라 게임 웹사이트fits into this discussion. However, in terms of its weight loss benefits, they are modest at best,바카라 게임 웹사이트 he said.
Berberine바카라 게임 웹사이트s possible side effects
Berberine can have side effects when mixed with other medications, including the medication , which is often prescribed for people with diabetes and polycystic ovary syndrome and, more recently, for weight loss.
바카라 게임 웹사이트Metformin lowers blood sugar, and berberine lowers blood sugar,바카라 게임 웹사이트 Levitt said. 바카라 게임 웹사이트And if you take two items that lower blood sugar at the same time, you could have a problem like excessive hypoglycemia, when blood sugar crashes.바카라 게임 웹사이트
In addition, berberine is 바카라 게임 웹사이트directly antimicrobial,바카라 게임 웹사이트 which was its most common use in historical herbal medicine, Levitt said: 바카라 게임 웹사이트Antimicrobial effects can irritate the GI tract so unless a person has an overgrowth of bad bugs it can cause digestive distress.바카라 게임 웹사이트
Berberine can be dangerous if taken with an immunosuppressive drug used to treat organ rejection post-transplant, as it might heighten that drug바카라 게임 웹사이트s effects and possible side effects. Another known interaction is with sedative drugs, as berberine can cause additional sleepiness and slowed breathing, according to the
In addition, berberine should not be taken while pregnant or breastfeeding.
바카라 게임 웹사이트Berberine can cross the placenta and might cause harm to the fetus. Kernicterus, a type of brain damage, has developed in newborn infants exposed to berberine,바카라 게임 웹사이트 the National Library of Medicine .
For these reasons, it바카라 게임 웹사이트s important to check with your doctor first if you바카라 게임 웹사이트re considering taking berberine or any other unregulated supplement.
Despite research investigating the herb바카라 게임 웹사이트s potential impact on diabetes, high cholesterol and heart disease, the FDA has 바카라 게임 웹사이트not yet approved berberine for any prescription or over-the-counter drug use, and it has sent notices of violation to companies that have made drug claims on their Web sites,바카라 게임 웹사이트 according to the
